Research Paper Volume 12, Issue 11 pp 10129—10146

Clusterin exerts a cytoprotective and antioxidant effect in human osteoarthritic cartilage

class="figure-viewer-img"

Figure 1. Histopathological features of OA articular cartilage. (A) Representative macroscopic images of fractured and OA femoral head samples (left panel) and Haematoxylin&Eosin-stained sections of articular cartilage at low and high magnification (center and right panel). (B) Representative images at different magnification of Alcian blue-PAS staining and (C) alcianophilia in the extracellular matrix of articular cartilage of fractured (n=30 donors; blue bars) and OA patients (n=30 donors; green bars). Abbreviations: A.U., arbitrary units. Mann-Whitney’s U-test: P < 0.0001.