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Online ISSN: 1945-4589
Research Paper
|
Volume 12, Issue 11
|
pp. 10969–10982
P22077 inhibits LPS-induced inflammatory response by promoting K48-linked ubiquitination and degradation of TRAF6
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Figure 8
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Figure 8.
Schematic of the anti-inflammatory mechanism of P22077.
P22077 promotes K48-linked ubiquitination and degradation of TRAF6, and subsequently inhibits the LPS-induced NF-κB and MAPKs pathway to alleviate inflammation.
