Expression of Concern
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 12, Issue 11 pp 10873—10895
miR-137 prevents inflammatory response, oxidative stress, neuronal injury and cognitive impairment via blockade of Src-mediated MAPK signaling pathway in ischemic stroke
Figure 13. Up-regulation of miR-137 or inhibition of Src inhibits the secretion of inflammatory cytokines and the degree of oxidative stress in astrocytes. (A) The expression of inflammatory markers in astrocytes using ELISA; (B) quantitation of ROS in astrocytes for each treatment group using the DCFH-DA fluorescent probe. Measurement data were expressed as mean ± standard deviation and compared using one-way ANOVA, followed by Tukey's post hoc test. * p < 0.05 vs. normal astrocytes; # p < 0.05 vs. OGD-induced astrocytes treated with negative controls; & p < 0.05 vs. astrocytes treated with miR-137 inhibitor. The experiment was repeated 3 times independently.