Research Paper Volume 12, Issue 11 pp 10809—10826
LncRNA and mRNA expression profiles reveal the potential roles of lncRNA contributing to regulating dural penetration in clival chordoma
Figure 6. Functional predictions of the lincRNAs based on pathway analysis of their adjacent coding-genes within 300 kb in the genome. (A) Schematic representation of lincRNA. (B, C) The pathway analysis applied for 22 mRNAs that were adjacent with 24 lincRNAs and showed the 4 down-regulated and 3 up-regulated pathways related to dural penetration of chordoma (P < 0.05). (D–G) The 17 lincRNAs and their adjacent coding genes are in the down-regulated pathways. (H–J) The 7 lincRNAs and their adjacent coding genes are in the up-regulated pathways.