Figure 6.Functional predictions of the lincRNAs based on pathway analysis of their adjacent coding-genes within 300 kb in the genome. (A) Schematic representation of lincRNA. (B, C) The pathway analysis applied for 22 mRNAs that were adjacent with 24 lincRNAs and showed the 4 down-regulated and 3 up-regulated pathways related to dural penetration of chordoma (P < 0.05). (D–G) The 17 lincRNAs and their adjacent coding genes are in the down-regulated pathways. (H–J) The 7 lincRNAs and their adjacent coding genes are in the up-regulated pathways.
