Research Paper Volume 12, Issue 11 pp 10809—10826

LncRNA and mRNA expression profiles reveal the potential roles of lncRNA contributing to regulating dural penetration in clival chordoma

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Figure 5. Schematic overviews of possible signaling pathways in which the 55 lncRNAs in the lncRNA-mRNA co-expression network participated. (A) The pathway analysis applied for 28 mRNAs that were aberrantly expressed in different degree of dural penetration of chordoma and co-expressed with 55 lncRNAs showed 5 down-regulated pathways (P < 0.05). (BE) Schematic overviews of the signaling pathways in which the 55 lncRNAs in the lncRNA-mRNA co-expression network probably participated. Red circles represent the location of 28 mRNAs predicted from co-expression network. Detailed descriptions of the lncRNAs and mRNAs are presented in Tables 14.