Research Paper Volume 12, Issue 11 pp 10809—10826
LncRNA and mRNA expression profiles reveal the potential roles of lncRNA contributing to regulating dural penetration in clival chordoma
Figure 5. Schematic overviews of possible signaling pathways in which the 55 lncRNAs in the lncRNA-mRNA co-expression network participated. (A) The pathway analysis applied for 28 mRNAs that were aberrantly expressed in different degree of dural penetration of chordoma and co-expressed with 55 lncRNAs showed 5 down-regulated pathways (P < 0.05). (B–E) Schematic overviews of the signaling pathways in which the 55 lncRNAs in the lncRNA-mRNA co-expression network probably participated. Red circles represent the location of 28 mRNAs predicted from co-expression network. Detailed descriptions of the lncRNAs and mRNAs are presented in