Research Paper Volume 12, Issue 11 pp 10427—10440

LncRNA PVT1 promotes exosome secretion through YKT6, RAB7, and VAMP3 in pancreatic cancer

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Figure 3. PVT1 promotes the movement of MVBs towards the plasma membrane. (A) Analysis of CD63 (red) in PVT1-overexpressing HS766T cells, as determined by confocal microscope. Nuclei were labeled with DAPI (blue). (B) Analysis of YKT6 (green) and CD63 (red) in PVT1-overexpressing HS766T cells, as determined by confocal microscope. (C) Exosomes in PVT1-overexpressing HS766T cells, as determined by electron microscope.