Figure 6C — Sigma-1 receptor is involved in diminished ovarian reserve possibly by influencing endoplasmic reticulum stress-mediated granulosa cells apoptosis

Research Paper|Volume 12, Issue 10|pp. 9041–9065

Sigma-1 receptor is involved in diminished ovarian reserve possibly by influencing endoplasmic reticulum stress-mediated granulosa cells apoptosis

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Figure 6C.The decrease of apoptosis rates in thapsigargin(TG)-induced ERS KGN cells treated with PRE-084/DHEA was accompanied by the decrease of ERS-related and apoptosis-related gene expression. (C) The mRNA expression of ERS and apoptosis-related genes in KGN cells treated with different drugs. *P<0.05.