Figure 6A-B — Sigma-1 receptor is involved in diminished ovarian reserve possibly by influencing endoplasmic reticulum stress-mediated granulosa cells apoptosis

Research Paper|Volume 12, Issue 10|pp. 9041–9065

Sigma-1 receptor is involved in diminished ovarian reserve possibly by influencing endoplasmic reticulum stress-mediated granulosa cells apoptosis

Back to articleFigure 6A-B(6 of 7)

100%

Figure 6A-B.The decrease of apoptosis rates in thapsigargin(TG)-induced ERS KGN cells treated with PRE-084/DHEA was accompanied by the decrease of ERS-related and apoptosis-related gene expression. (A) Apoptosis index in KGN cells treated with different drugs. (B) Flow cytometry sorting of sigma-1 receptor protein in KGN cells treated with different drugs.
(C) The mRNA expression of ERS and apoptosis-related genes in KGN cells treated with different drugs. *P<0.05.