Figure 3 — miR-195-5p alleviates acute kidney injury through repression of inflammation and oxidative stress by targeting vascular endothelial growth factor A

Research Paper|Volume 12, Issue 11|pp. 10235–10245

miR-195-5p alleviates acute kidney injury through repression of inflammation and oxidative stress by targeting vascular endothelial growth factor A

Back to articleFigure 3(3 of 7)

100%

Figure 3.Overexpression of miR-195-5p inhibited I/R-induced renal injury in vivo. (A) miR-195-5p expression in renal tissues. (B) Serum Cr levels in I/R rat models transfected with miR-195-5p mimics. (C) BUN levels in I/R rat models transfected with miR-195-5p mimics. (D) Representative micrographs of renal histologic findings. Scale bars = 20 μm. (E and F) Analysis of apoptosis using the TUNEL assay in renal tissues from AKI rats. Eight rats were used in each group. Three independent experiments were performed. Error bars represent the mean ± SD of at least three independent experiments. *P < 0.05.