Expression of Concern
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 12, Issue 9 pp 8301—8320
Long non-coding RNA CCAT1 promotes colorectal cancer progression by regulating miR-181a-5p expression
Figure 3. CCAT1 and miR-181a-5p was negative correlative. (A) The expression level of miR-181a-5p was upregulated by transfecting the miR-181a-5p mimics and was downregulated by transfecting the miR-181a-5p inhibitor into both HT-29 and HCT 116 cells. (B) After transfection of si-CCAT1-2 and si-CCAT1-1 in HT-29 and HCT 116 cells, the expression of miR-181a-5p was significantly upregulated. (C) Transfection of miR-181a-5p mimics or inhibitor could not reversely affect the expression of CCAT1. (D) The correlation between CCAT1 and miR-181a-5p expression level was measured in 50 CRC tissues. All assays were performed three times. **P<0.01, compared with NC group.