Identification and validation of the angiogenic genes for constructing diagnostic, prognostic, and recurrence models for hepatocellular carcinoma

Jinyu Zhu; Bufu Tang; Jie Li; Yueli Shi; Minjiang Chen; Xiuling Lv; Miaomiao Meng; Qiaoyou Weng; Nannan Zhang; Kai Fan; Min Xu; Jiansong Ji

doi:doi:10.18632/aging.103107

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Research Paper Volume 12, Issue 9 pp 7848—7873

Identification and validation of the angiogenic genes for constructing diagnostic, prognostic, and recurrence models for hepatocellular carcinoma

Figure 10. Molecular docking and pharmacophore models for targeted drug identification. (A) The 3D structure of piperlongumine was obtained from the PubChem database (https://pubchem.ncbi.nlm.nih.gov). (B–D) Specific binding site of piperlongumine and EGF (B), EGFR (C) and MMP3 (D). (E, F) The pharmacophore model of EGFR (E) and MMP3 (F).