Research Paper Volume 12, Issue 7 pp 6401—6414

Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice

class="figure-viewer-img"

Figure 3. Spermidine and spermine attenuates oxidative stress in SAMP8. (A) The level of MDA in brain. (B) The level of ROS in the brain. Data represent mean ± SEM (n = 6 per group). #P < 0.05, ##P < 0.01, ###P < 0.001 vs. SAMR1; *P < 0.05, **P < 0.01, ***P < 0.001 vs. SAMP8.