Klotho antagonizes pulmonary fibrosis through suppressing pulmonary fibroblasts activation, migration, and extracellular matrix production: a therapeutic implication for idiopathic pulmonary fibrosis

Qiqing Huang; Yan Chen; Shaoran Shen; Yuanyuan Wang; Liya Liu; Shuangshuang Wu; Wei Xu; Weihong Zhao; Mingyan Lin; Jianqing Wu

doi:doi:10.18632/aging.102978

← Back

Research Paper Volume 12, Issue 7 pp 5812—5831

Klotho antagonizes pulmonary fibrosis through suppressing pulmonary fibroblasts activation, migration, and extracellular matrix production: a therapeutic implication for idiopathic pulmonary fibrosis

Figure 2. Functional interaction network reveals the most likely pathways that could be regulated by KL in IPF. Functional interaction network generated by the STRING database for the top 200 genes highly correlated with KL in BROWN module, with nodes representing genes and edges representing interactions. Disconnected genes were not shown.