Research Paper Volume 12, Issue 6 pp 5121—5139

EMMPRIN/CD147 plays a detrimental role in clinical and experimental ischemic stroke

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Figure 1. GFAP positive astrocytes co-localize with CD147. (A) Representative image of cresyl violet stained brain slice showing peri-infarct regions where imaging was performed. (B) Representative 20x IHC images of sham and stroke brain slices. CD147 co-localizes with GFAP positive astrocytes in the peri-infarct region. Pearson’s correlation coefficient <0.0001, SH 0.14±0.02 vs. ST 0.73±0.03, n=6.