Research Paper Volume 12, Issue 6 pp 5031—5047

Figure 6. Molecular signatures associated with TET3 in AML. (A) Expression heatmap of differentially expressed genes between TET3^low and TET3^high AML patients (FDR<0.05, P<0.05 and |log2 FC|>1.5). (B) Volcano plot of differentially expressed genes between TET3^low and TET3^high AML patients. (C) Gene Ontology analysis of DEGs conducted using online website of STRING (http://string-db.org). (D) Venn results of microRNAs which could target TET3 predicted by DIANA (http://diana.imis.athena-innovation.gr/DianaTools/index.php? r=microT_CDS/index), miRDB (http://mirdb.org/miRDB/), mirDIP (http://ophid.utoronto.ca/mirDIP/), TargetScan (http://www.targetscan. org/vert_72/), and miRWalk (http://mirwalk.umm.uni-heidelberg.de/).