Research Paper Volume 12, Issue 2 pp 1899—1909
Inhibition of miR-193a-3p protects human umbilical vein endothelial cells against intermittent hypoxia-induced endothelial injury by targeting FAIM2
Figure 5. Effects of miR-193a-3p inhibition in HUVECs under IH condition are reversed by knockdown of FAIM2. miR-193a-3p inhibitor, si-FAIM2, and corresponding scrambled control were transfected into HUVECs. Cells without transfection were served as control. (A) Cell viability. (B, C) Western blot assays of FAIM2, Bcl-2, Bax, and Caspase-3 protein. β-Actin was served as internal control. IH: intermittent hypoxia; n = 3. (Data are presented as the mean ± SD of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001).