Research Paper Volume 12, Issue 1 pp 866—883

Figure 2. Kaplan Meier survival plot of ccRCC patients in TCGA database according to high and low mRNA expression of six EMT related genes. CDH1 mRNA expression was associated with both worse progression-free survival (p=0.015) and worse overall survival (p=0.003) of ccRCC patients (A, G); CDH2 mRNA expression was not an indicator of either progression-free survival (p=0.593) or overall survival (p=0.075) of ccRCC patients (B, H); Higher SNAI1 mRNA expression was moderately associated with both worse progression-free survival (p=0.054) and worse overall survival (p=0.010) of ccRCC patients (C, I); SNAI2 mRNA expression was not an indicator of either progression-free survival (p=0.105) or overall survival (p=0.242) of ccRCC patients (D, J); Higher VIM mRNA expression was associated with both worse progression-free survival (p<0.001) and worse overall survival (p=0.005) of ccRCC patients (E, K); Higher TWIST1 mRNA expression was associated with both worse progression-free survival (p<0.001) and worse overall survival (p<0.001) of ccRCC patients (F, L).