Figure 1. Cross-sectional meta-analysis results for FEV1 of males and females in SAPALDIA and ECRHS. (A) Mean change in FEV1 (mL) per year of intrinsic epigenetic age acceleration at baseline; (B) Mean change in FEV1 (mL) per year of intrinsic epigenetic age acceleration at follow-up. The estimates have been measured with 95% confidence interval in mL/year.