Figure 6. PAX8 expression was upregulated in HCC tissues. (A) PAX8 expression was higher in HCC tissues than in nontumor tissues. (B) Compared to adjacent normal samples, 75% (30 of 40) of HCC samples showed overexpression of PAX8. (C) PAX8 was overexpressed in four HCC cell lines (QGY-7703, SMMC7721, MHCC-97H and HepG2) compared to the hepatocyte cell line (HL-7702). (D) PAX8 expression was positively correlated with MACC1-AS1 expression in HCC samples. ***p<0.001.