A phenolic amide (LyA) isolated from the fruits of <i>Lycium barbarum</i> protects against cerebral ischemia–reperfusion injury via PKCε/Nrf2/HO-1 pathway

Kai Gao; Meiyou Liu; Yi Ding; Minna Yao; Yanrong Zhu; Jinyi Zhao; Lianghua Cheng; Juan Bai; Fan Wang; Jinyi Cao; Jiankang Li; Haifeng Tang; Yanyan Jia; Aidong Wen

doi:doi:10.18632/aging.102578

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Research Paper Volume 11, Issue 24 pp 12361—12374

A phenolic amide (LyA) isolated from the fruits of Lycium barbarum protects against cerebral ischemia–reperfusion injury via PKCε/Nrf2/HO-1 pathway

Figure 3. LyA Promoted the Expression of Nrf2 and HO-1. (A) Protein expressions of Nuclear Nrf2, Cytoplasmic Nrf2 and HO-1 were evaluated by Western blot analysis. (B) The immunofluorescence staining of Nrf2 with DAPI (400 x). Data were presented as mean ± SD (n = 6). ^* p < 0.05 compared with I/R group.