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Figure 8
Figure 8.Schematic diagram of endogenous competition mechanism. CircSMO742 and SMO mRNA derived from a parent gene of SMO and circSMO742 circled from 4 exons. In glioma, circSMO742 was up-regulation could sponge miR-338-3p a lot to let parent gene largely coding SMO mRNA, encoding SMO protein to promote cell proliferation, migration and invasion.