Research Paper Volume 12, Issue 1 pp 53—69

FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors

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Figure 7. Mechanism of FHL3 in regulation of EMT process. Protein which involved in signaling: AKT (AKT, ser437-AKT), GSK3β (GSK3β, ser9-GSK3β, try216-GSK3β), FHL3, snail1, twist1, TGFβ1, smad (smad2/3, smad4), and E-cadherin.