CircRNA AFF4 promotes osteoblast cells proliferation and inhibits apoptosis via the Mir-7223-5p/PIK3R1 axis
Figure 7.Mechanisms of circRNA AFF4 mediated fracture healing. CircRNA AFF4 acts as sponge of miR-7223-5p, leading to PI3K-AKT activation, which accelerates fracture healing via promoting cell proliferation and inhibiting apoptosis.