Figure 8 — Neuroprotective effects of protocatechuic aldehyde through PLK2/p-GSK3β/Nrf2 signaling pathway in both in vivo and in vitro models of Parkinson's disease

Research Paper|Volume 11, Issue 21|pp. 9424–9441

Neuroprotective effects of protocatechuic aldehyde through PLK2/p-GSK3β/Nrf2 signaling pathway in both in vivo and in vitro models of Parkinson's disease

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Figure 8.PCA increased the expressions of PLK2 and activated p-GSK3β/Nrf2 pathway in MPP⁺-incubated SH-SY5Y cells. (A) Representative western blot bands of PLK2, α-Syn, p-GSK3β, GSK3β, Nrf2, tubulin and Histone H3. (B–E) Quantification of PLK2, p-GSK3β/ GSK3β and nucleus Nrf2 levels in cells. Data were presented as mean ± S.D., n = 6; ^*P < 0.05 vs. control group; ^#P< 0.05 vs. MPP⁺group.