Figure 4 — Probucol, a “non-statin” cholesterol-lowering drug, ameliorates D-galactose induced cognitive deficits by alleviating oxidative stress via Keap1/Nrf2 signaling pathway in mice

Research Paper|Volume 11, Issue 19|pp. 8542–8555

Probucol, a “non-statin” cholesterol-lowering drug, ameliorates D-galactose induced cognitive deficits by alleviating oxidative stress via Keap1/Nrf2 signaling pathway in mice

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Figure 4.Effect of Prob on ROS and MDA level, and the activities of SOD and GSH-PX. (A–C) MDA level and the activities of SOD and GSH-PX in plasma, respectively. (D–G) Level of ROS and MDA, and the activities of SOD and GSH-PX in plasma, respectively. Data in each experiment represent mean ± SEM from 10 independent samples. Statistically significant differences were calculated by one-way ANOVA using the SPSS 20.0 software. *P<0.05 and ** P<0.01, versus D-gal group.