Figure 2 — Dopaminergic neuron injury in Parkinson’s disease is mitigated by interfering lncRNA SNHG14 expression to regulate the miR-133b/ α-synuclein pathway

Research Paper|Volume 11, Issue 21|pp. 9264–9279

Dopaminergic neuron injury in Parkinson’s disease is mitigated by interfering lncRNA SNHG14 expression to regulate the miR-133b/ α-synuclein pathway

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Figure 2.The binding between SP-1 and SNHG14 promoter was influenced by rotenone. Clonal mesencephalic DA cell line MN9D cells were treated with 1μmol/L rotenone. (A) SP-1 protein level in MN9D cells was determined by western blotting. (B) The binding activity of SP-1 to the promoter of SNHG14 was evaluated with chromatin immunoprecipitation (ChIP) assay. **P<0.01 compared with control.