Figure 1. Identification of differentially expressed miRNAs in osteosarcoma. (A) Heat map summarizing the results of a microarray analysis. (B) Real time PCR analysis of miRNA expression in osteosarcoma tissues and adjacent tissues. ** P< 0.05 vs. adjacent tissues. (C) Relationship between miR-627-3p expression and the survival period among osteosarcoma patients. (D) Real time PCR analysis of miR-627-3p expression in hFOB 1.19, HOS, U2OS and MG63 cells. ** P< 0.05 vs. hFOB 1.19 cells.