Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2

Lei Yu; Si Gui; Yawei Liu; Xiaoyu Qiu; Guozhong Zhang; Xi’an Zhang; Jun Pan; Jun Fan; Songtao Qi; Binghui Qiu

doi:doi:10.18632/aging.102092

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Research Paper Volume 11, Issue 15 pp 5300—5318

Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2

Figure 11. MSCs-derived exosomes deliver miR-199a to glioma cells inhibiting the proliferation, migration and invasion of glioma cells, as well as enhancing the chemosensitivity by down-regulating AGAP2.