Figure 7.Schematic model of the antitumor actions of GDF10 on TNBC cells. GDF10 expression increases Smad7 levels and inhibits the formation of Smad2/4 complexes. Overexpression of GDF10 suppresses proliferation, EMT, and invasion in TNBC cells via inhibiting the formation of Smad2/4 involving the upregulation of Smad7.
