<i>LINC00857</i> knockdown inhibits cell proliferation and induces apoptosis via involving STAT3 and MET oncogenic proteins in esophageal adenocarcinoma

Wenmei Su; Lihui Wang; Feiyu Niu; Lei Zou; Chunfang Guo; Zhuwen Wang; Xiao Yang; Jiancong Wu; Yi Lu; Jian Zhang; David G. Beer; Zhixiong Yang; Guoan Chen

doi:doi:10.18632/aging.101953

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Research Paper Volume 11, Issue 9 pp 2812—2821

LINC00857 knockdown inhibits cell proliferation and induces apoptosis via involving STAT3 and MET oncogenic proteins in esophageal adenocarcinoma

Figure 3. SiRNA-mediated knockdown of LINC00857 inhibits EAC cell migration and invasion. (A) Migration was decreased after LINC00857 siRNA transfection of OE33 and FLO1 cells. (B) The bar chart represented the count number of migration cells. (C) Invasion was decreased after LINC00857 siRNA transfection of OE33 and FLO1 cells. (D) The bar chart represented the count number of invasion cells. Values represented the mean ± s.d. from three independent experiments. *p < 0.05, **p < 0.01.