Figure 3 — Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice

Research Paper|Volume 11, Issue 8|pp. 2457–2476

Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice

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Figure 3.Behavioral evaluation of 14-month-old Tbk1-NKO mice. (A–B) Latency to reach the platform and number of target quadrant crosses in the Morris water maze (n = 9-10). *P < 0.05, compared to WT control. (C–D) Swimming distances and body weight (n = 9-10). *P < 0.05, compared to WT mice.