The acute transcriptional response to resistance exercise: impact of age and contraction mode

Colleen S. Deane; Ryan M. Ames; Bethan E. Phillips; Michael N. Weedon; Craig R.G. Willis; Catherine Boereboom; Haitham Abdulla; Syed S.I. Bukhari; Jonathan N. Lund; John P. Williams; Daniel J. Wilkinson; Kenneth Smith; Iain J. Gallagher; Fawzi Kadi; Nathaniel J. Szewczyk; Philip J. Atherton; Timothy Etheridge

doi:doi:10.18632/aging.101904

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Research Paper Volume 11, Issue 7 pp 2111—2126

The acute transcriptional response to resistance exercise: impact of age and contraction mode

Figure 1. Concentric and eccentric exercise induce a common transcriptomic response in young and older muscle. Overlap of contraction mode-associated differentially expressed genes within age groups. Near complete overlap exists between up-regulated (top left Venn) and down-regulated (top right Venn) genes, 5 h after concentric and eccentric exercise in young muscle. Up-regulated (bottom left Venn) and down-regulated (bottom right Venn) genes in older muscle after concentric and eccentric exercise also display predominant overlap.