Autophagy delays progression of the two most frequent human monogenetic lethal diseases: cystic fibrosis and Wilson disease
Figure 1.Autophagy in cystic fibrosis and Wilson disease. The relationship between autophagy and CFTR mutations in cystic fibrosis (A) or ATP7B mutations in Wilson disease (B) are depicted. BECN1, Beclin 1; TGM2, transglutaminase 2.