Figure 4. Overexpression of miR-542-3p suppressed cell migration and invasion in osteosarcoma cells. (A) Wound-healing assay was performed to determine the migratory capacity of 143B and U-2OS cells transfected with water (blank) or scramble miRNA (NC) or miR-542-3p mimics or inhibitors, respectively. **P<0.01 compared with the NC group; (B) Transwell assay was performed to determine the invasive capacity of 143B and U-2OS cells transfected with water (blank) or scramble miRNA (NC) or miR-542-3p mimics or inhibitors, respectively. **P<0.01 compared with the NC group.