Figure 3 — Sevoflurane impairs learning and memory of the developing brain through post-transcriptional inhibition of CCNA2 via microRNA-19-3p

Research Paper|Volume 10, Issue 12|pp. 3794–3805

Sevoflurane impairs learning and memory of the developing brain through post-transcriptional inhibition of CCNA2 via microRNA-19-3p

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Figure 3.SEVO upregulates miR-19-3p in neuron cells. (A) RT-qPCR for 18 CCNA2-targeting miRNAs in HCN-2 cells exposed to either 5% SEVO or CTL gas. (B-C) Bioinformatics analysis showed predictive binding of miR-19-3p onto 3’-UTR of CCNA2 mRNA of rat (B) and human (C). N=5.