Figure 7 — Autophagy of macrophages is regulated by PI3k/Akt/mTOR signalling in the development of diabetic encephalopathy

Research Paper|Volume 10, Issue 10|pp. 2772–2782

Autophagy of macrophages is regulated by PI3k/Akt/mTOR signalling in the development of diabetic encephalopathy

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Figure 7.Schematic. Diabetes induces increases in brain inflammatory macrophages, through increased PI3k/AKT/mTOR/S6K1 signalling and suppression of autophagy. mTOR and autophagy inhibit each other. RAP inhibits mTOR. CQ inhibits autophagy.