Figure 8 — Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice

Research Paper|Volume 10, Issue 5|pp. 1027–1052

Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice

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Figure 8.Glucose and insulin metabolism in 15-month-old WT and KO mice. (a) Glucose tolerance curves (b) area under the curve (c) fed blood glucose (d) fasting circulating insulin levels. (e) Plasma resistin levels. WT^AL, n = 8; WT^DR, n = 6; KO^AL, n = 14; KO^DR, n = 10. Error bars represent mean ± SEM. * represents significant effect of treatment and ‡ represents significant effect of genotype. ‡ p < 0.05; **/‡‡ p < 0.01.