Figure 2. Colonic crypt length in dwarf mice. H&E staining sections of proximal colon (PC) and distal colon (DC) were used for evaluation of colonic crypt length. (A) Juvenile mice. Left panel, images of colonic crypts; right panel, cryptic cell number from 40 integrated crypts per mouse. (B) Adult mice. Left panel, images of colonic crypts; right panel, cryptic cell number from 40 integrated crypts per mouse. N=5; ***, P < 0.001 compared to WT. Scare bar: 50μm.