Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936

Sarah E. Harris; Valentina Riggio; Louise Evenden; Tamara Gilchrist; Sarah McCafferty; Lee Murphy; Nicola Wrobel; Adele M. Taylor; Janie Corley; Alison Pattie; Simon R. Cox; Carmen Martin-Ruiz; James Prendergast; John M. Starr; Riccardo E. Marioni; Ian J. Deary

doi:doi:10.18632/aging.101333

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Research Paper Volume 9, Issue 12 pp 2489—2503

Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936

Figure 3. Manhattan plot of the P-values of the transcriptome-wide association analyses for (a) smoking status (current versus never) and (b) telomere length. The red line indicates the threshold for transcriptome-wide significance (P<2.17x10^-6).