Figure 2. LRSAM1 was down-regulated in HSCR samples. (A) The expression of LRSAM1 significantly decreased in HSCR (n=80) tissues compared with control samples (n=80) in mRNA level. No significant difference of LNX2 or UBE2D3 was observed between HSCR and control. (B) The protein expression level of LRSAM1 in HSCR tissues and controls. *indicates significant difference compared with control group, P<0.05.