Figure 5 — HIF-1–dependent regulation of lifespan in Caenorhabditis elegans by the acyl-CoA–binding protein MAA-1

Research Paper|Volume 9, Issue 7|pp. 1745–1769

HIF-1–dependent regulation of lifespan in Caenorhabditis elegans by the acyl-CoA–binding protein MAA-1

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Figure 5.DAF-16 is required for lifespan extension in maa-1–deficient animals. Lifespan of maa-1(ok2033); daf-16(mu86) double mutants is significantly shorter than that of maa-1(ok2033) single mutants (P<0.0001). P values were calculated using the log-rank (Mantel-Cox) method. Replicate experiments and additional statistical analysis are shown in Table S1 and S2.