Research Paper Volume 8, Issue 12 pp 3468—3485
Naked mole-rats maintain healthy skeletal muscle and Complex IV mitochondrial enzyme function into old age
Figure 5. No significant difference in Complex IV activity is observed during aging. Cytochrome c Oxidase activity (COX, in brown) is observed consistently in adolescent (A), young adult (B), and aged adult (C) NMR skeletal muscle tissue (quadriceps). A small number of COX-deficient cells (in blue) are observed in aged adults; this number does not significantly increase with age (D, p > 0.05, two-tailed t-test). Similar patterns were observed in colon tissue (E-H) and cardiac muscle (I-L).