Figure 2.Gene expression of matrix remodeling enzymes in young and old livers. Hepatic gene expression of Mmp2, Mmp3, Mmp8, Mmp9, Mmp13, Mmp14, Timp1, Timp2 and Cxcl9 in control and CCl4-treated young and old mice (Mean ± SEM) (n=6/group). Statistical analysis was performed by two-way ANOVA for repeated measures (boxes) followed by Bonferroni’s post-hoc correction. **P<0.01; ***P<0.001 for differences between age groups.