Research Paper Volume 8, Issue 12 pp 3341—3355

Effects of dietary restriction on adipose mass and biomarkers of healthy aging in human

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Figure 6. Changes of circulating IGFB-1, IGFBP-2 and IGFBP-3 after DR. Studies were stratified according to the design of the study. A standardized difference in mean (SDM) indicates an increase, whereas a negative SDM indicates the decrease of IGFB-1, IGFBP-2 or IGFBP-3. The empty black square indicates the results of each study, whereas empty blu square shows the summary results of each subgroup data. The red diamond resumes overall results of the included studies in the forest plot.