Research Paper Volume 8, Issue 11 pp 3065—3090
Mast cells and histamine are triggering the NF-κB-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation
Figure 4. Effects of LPS-induced acute inflammation on activation of NF-κB signaling in mesentery close to mesenteric lymphatic vessels in adult (9 mo, n=4 for control and n=4 for LPS-treated groups) and aged (24 mo, n=4 for control and n=4 for LPS-treated groups) rats. Left panels – representative images of mesentery labeled for phospho-NF-κB p65 (in red) in sham (ctrl) and LPS-treated (LPS) mesenteric segments of both ages. The graph on the right shows a comparison of pixel intensity of phospho-NF-κB p65 per 100 μm2 under the various conditions. * indicates significant difference (p < 0.05, one-way ANOVA) between control and LPS-treated mesenteric segments within each age group. # indicates significant difference (p < 0.05, one-way ANOVA) between adult and aged mesenteric segments under control conditions.