Nickel chloride (NiCl2) in hepatic toxicity: apoptosis, G2/M cell cycle arrest and inflammatory response

Hongrui Guo; Hengmin Cui; Jing Fang; Zhicai Zuo; Junliang Deng; Xun Wang; Ling Zhao; Kejie Chen; Jie Deng

doi:doi:10.18632/aging.101108

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Research Paper Volume 8, Issue 11 pp 3009—3027

Nickel chloride (NiCl2) in hepatic toxicity: apoptosis, G2/M cell cycle arrest and inflammatory response

Figure 6. Changes of the cell cycle in the liver. (A) Representative flow cytometric diagram of cell cycle analysis. (B) Changes of the percentage of G₀/G₁, G₂/M, and S phase in the liver. (C) Changes of the G₂/M phase regulators mRNA expression levels. Data are presented with the mean ± standard deviation (n=5). *P<0.05, compared with the control group. **P<0.01, compared with the control group.