Figure 1. Histopathological changes in the liver at 42 days of age. Control group: No changes are observed; 300 mg/kg group: Hepatic cells show slight granular and vacuolar degeneration; 600 mg/kg group: Hepatic cells show granular, vacuolar and fatty degeneration. 900 mg/kg group: Hepatic cells show marked granular, vacuolar and fatty degeneration. (H·E).