Research Paper Volume 8, Issue 11 pp 2814—2826
Caloric restriction preserves memory and reduces anxiety of aging mice with early enhancement of neurovascular functions
Figure 2. Caloric restriction enriches vascular signaling markers and shifts metabolism in young mice. (A) Western blotting (WB) of mTOR, eNOS, P-gp and GLUT1 from the cortical vasculature, β-Actin was used as loading control; corresponding values of (B) mTOR, (C) eNOS, (D) P-gp, and (E) GLUT1 between the young AL and CR mice. All the WB data were normalized to β-Actin and compared to young AL (100%). (F) Blood glucose and (G) Blood Ketone levels of the mice. *p < 0.05; **p < 0.01; ***p < 0.001; AL: ad libitum; CR: caloric restriction.