Research Paper Volume 8, Issue 10 pp 2590—2602
Haploinsufficiency of the Myc regulator Mtbp extends survival and delays tumor development in aging mice
Figure 1. Mtbp heterozygosity increases longevity. (A-C) Kaplan-Meier survival curves of Mtbp+/+ (+/+) and Mtbp+/- (+/-) mice with the number of mice in each group denoted by n. p value determine by log-rank tests. (D) All, male, and female Mtbp+/- mice in the indicated decile or quartile of the mouse cohort. (E) Instantaneous death rate plotted; log-rank p=0.0013, Chi-sq=10.27, df=1; number of mice in each group denoted by n.