This article has been retracted. Aging (Albany NY). 16:12104-12104 . https://doi.org/10.18632/aging.205987  PMID: 27777383
Research Paper Volume 8, Issue 10 pp 2509—2524

MicroRNA-346 facilitates cell growth and metastasis, and suppresses cell apoptosis in human non-small cell lung cancer by regulation of XPC/ERK/Snail/E-cadherin pathway

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Figure 9. miR-346 directly targeting XPC and then activating ERK/Snail pathway, which leads to decrease of E-cadherin. (A-B) Expression of XPC, phospho-ERK1/2, ERK2, Snail, and E-cadherin were detected in A549 and spc-a-1 cells either transiently transfected with NC, miR-346, si-XPC, or ASO-346. The intensity of XPC, phospho-ERK1/2, ERK2, Snail, and E-cadherin bands were quantified using Image J. Assays were performed in triplicate. *P < 0.05. Means ± SEM was shown. Statistical analysis was conducted using ANOVA.